Washing face in afternoon, do I need to again before bed?

I use a mild cleanser to wash my face, and use this in the morning. I wear makeup to work, which ends around 1, and the days I'm just home afterwards I wash my makeup off when I get home (using the same mild cleanser). My question is: Do I need to wash my face again before going to bed? I have heard that washing your face more than twice a day can strip skin of it's natural oils and even cause more acne. Is it worse for me to be washing my face 3 times a day? OR Washing it twice (morning and afternoon) but not before bed? OR Washing in morning, wearing makeup all day, then washing before bed? Either way, I NEVER go to bed with makeup on, of course.