What is the best thing to take for hip and knee muscle spasms at night and what could this be from?

I have been having problems with the muscles in my shoulders for several years and muscles in my jaw stated about a year ago. And now I am having muscle spasms in my knee and hip at night. And is unbearable. I am really fatigued I don't know if it's from something else or all related. I my hands shake really bad too when this all started too